Biologist Amro Hamdoun on keeping out the bad guys

Clearly, PopTech Science and Public Leadership Fellow Amro Hamdoun’s communication training is paying off. Casting aside his data-dense, rather intimidating charts and graphs of how chemicals affect cell structure, he instead showed the laughing crowd a menacing photo of a muscle-bound man in black suit. “Your cells,” explained Hamdoun, “have bouncers.”

The impact of chemicals on cell structure, however, is no laughing matter. With over 85,000 chemicals produced in the last century, the average person now has between 300-500 of miscellaneous chemicals in their systems. It’s the “bouncers”, officially known as multi-drug transporters, that work to keep the bad guys out. The question is, why do some of the “bad” chemicals make it into the cells and how can we predict which ones will do so (with averse and often unknown consequences) as we develop even more chemicals?

Science and Public Leadership Fellows Amro Hamdoun (right) and Gidon Eshel (left)

Hamdoun, a cell biologist, focuses his research specifically on embryos using sea urchins for test subjects: one sea urchin can produce roughly a million eggs in ten minutes, which is comparable to the reproduction efforts of 5,000 mice. The goal of his research? To ensure cells can keep out the bad chemicals and thereby prevent birth defects and other anomalies of embryonic growth.

To learn more about his work, Hamdoun invites the PopTech community to check out

(Photo: Science and Public Leadership Fellows Amro Hamdoun (right) and Gidon Eshel (left). Photo credit: John Santerre)

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